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What is SCLERODERMA?

A Connective Tissue Disease

Systemic sclerosis, or scleroderma is one of several connective tissue diseases. It can impact your1,2:

Skin
Skin
Internal organs
Internal organs
Connective Tissue:
Cartilage
Cartilage
Bones
Bones
Tendons
Tendons
Ligaments
Ligaments
Examples of other connective tissue diseases include3:
Rheumatoid arthritis
Mixed connective tissue disease
Systemic lupus erythematosus

Types of Scleroderma

There are 2 main types of scleroderma1,2:

Localized Scleroderma
primarily affects only
Skin
Scleroderma
types
Systemic Sclerosis
affects
Skin
Blood vessels
Major organs
More Than a Skin Condition

More Than a Skin Condition

Scleroderma is not just a skin condition. It can also cause serious lung complications such as pulmonary arterial hypertension, or PAH for short.4,5

What Is PAH?

Scleroderma can cause serious lung complications like PAH.4

Learn more

Get Screened for PAH

Screening tests can detect signs of PAH that you may not be able to feel.6

Read more
References: 1. Cleveland Clinic. Connective tissue diseases. Accessed August 25, 2021. https://my.clevelandclinic.org/health/diseases/14803-connective-tissue-diseases 2. Johns Hopkins Medicine. Types of scleroderma. Accessed November 11, 2021. https://www.hopkinsmedicine.org/health/conditions-and-diseases/scleroderma/types-of-scleroderma 3. Zanatta E, Polito P, Famoso G, et al. Pulmonary arterial hypertension in connective tissue disorders: pathophysiology and treatment. Exp Biol Med. 2019;244(2):120-131. 4. Fischer A, Bull TM, Steen VD. Practical approach to screening for scleroderma-associated pulmonary arterial hypertension. Arthritis Care Res (Hoboken). 2012;64(3):303-310. 5. Mandras SA, Ventura HO, Corris PA. Breaking down the barriers: why the delay in referral for pulmonary arterial hypertension? Ochsner J. 2016;16(3):257-262. 6. Khanna D, Gladue H, Channick R, et al. Recommendations for screening and detection of connective-tissue disease associated pulmonary arterial hypertension. Arthritis Rheum. 2013;65(12):3194-3201.